Progress of traditional Chinese medicine monomers in the treatment of respiratory diseases by intervening nucleotide binding and oligomerization domain-like receptor protein 3 inflammasome
10.13699/j.cnki.1001-6821.2024.12.030
- VernacularTitle:中药单体干预核苷酸结合寡聚化结构域样受体蛋白3炎性小体治疗呼吸系统疾病的研究现状
- Author:
Hua-Yang PAN
1
;
Xu-Ming LUO
;
Fu-Qi MA
;
Zhen-Hua NI
;
Xiong-Biao WANG
;
Yu-Hua LIN
Author Information
1. 上海中医药大学附属普陀医院呼吸科,上海 200062
- Keywords:
Chinese herbal monomers;
respiratory disease;
nucleotide binding and oligomerization domain-like receptor protein 3 inflammasome;
treatment by Chinese herbs;
inflammation
- From:
The Chinese Journal of Clinical Pharmacology
2024;40(12):1839-1843
- CountryChina
- Language:Chinese
-
Abstract:
Adequate inflammation can effectively eliminate harmful substances and prevent disease as a self-protective measure to prevent further damage to the body,while abnormally activated inflammation is detrimental to the body.Nucleotide binding and oligomerization domain-like receptor protein 3(NLRP3)inflammasome that participates in inflammatory responses are closely related to many physiological and pathological processes and play an important role in the occurrence and development of pulmonary diseases.This article mainly reviewed the activation mechanism and hypothesis of NLRP3 inflammasome,as well as the research on treating respiratory diseases by interfering with NLRP3 inflammasome.
