Research stauts of mRNA vaccines in cancer and infectious diseases
10.13699/j.cnki.1001-6821.2024.11.027
- VernacularTitle:mRNA疫苗在癌症和传染性疾病方面的研究现状
- Author:
Can LI
1
;
Shuang LIU
;
Xue ZHANG
Author Information
1. 佳木斯大学基础医学院微生物-免疫调节网络与相关疾病重点实验室,黑龙江佳木斯 154000
- Keywords:
mRNA vaccines;
cancer;
infectious diseases;
delivery sys-tems
- From:
The Chinese Journal of Clinical Pharmacology
2024;40(11):1665-1669
- CountryChina
- Language:Chinese
-
Abstract:
With the advantages of high efficiency,safety,potential for rapid development,and cost-effectiveness,mRNA vaccines have become a powerful therapeutic platform for cancer and infectious diseases.The shortcomings of mRNA vaccines,such as instability and low in vivo delivery efficiency,have been effectively improved by structural modification of mRNA vaccines and delivery improvement.Based on the currently approved mRNA vaccines and clinical trials of mRNA vaccines,this paper reviews the classification,structural modification,mechanism of action,and applications of mRNA vaccines in cancer and infectious diseases,and discusses the current challenges and future development prospects of mRNA vaccines.
