Gadopiclenol,a new radiological diagnostic drug used in magnetic resonance imaging

VernacularTitle:用于核磁共振成像检查的放射性诊断新药
Author: Lu ZHENG ^{1
,

2} ; Ting YANG ; Chao-Yang CHEN ; Ran WEI ; Xuan-Ling ZHANG ; Jing-Zhong DENG ; Ying ZHOU
Author Information

1. 北京大学第一医院药剂科,北京 100034
2. 北京大学第一医院太原医院药剂科,山西太原 030000
Keywords: Gadopiclenol; magnetic resonance imaging; radiological diagnostic; gadolinium-based contrast agent
From: The Chinese Journal of Clinical Pharmacology 2024;40(11):1661-1664
CountryChina
Language:Chinese
Abstract: Gadopiclenol was used in adults and pediatric patients 2 years of age and older during magnetic resonance imaging(MRI)to detect and view lesions of the central nervous system(brain,spine,and associated tissues)and body(head and neck,chest,abdomen,pelvis,and musculoskeletal system)with abnormal vascular properties.Gadopiclenol is a new type of macrocyclic gadolinium-based contrast agent(GBCA).In this article,the molecular structure,principle of action,pharmacodynamics,pharmacokinetics,clinical studies,safety and other aspects of Gadopiclenol were reviewed,in order to introduce the current research status and existing achievements of Gadopiclenol.