Role of intestinal flora in hypertension complicated with osteoporosis
10.13699/j.cnki.1001-6821.2024.03.030
- VernacularTitle:肠道菌群在高血压合并骨质疏松症中的作用
- Author:
Mei-Long SI
1
;
Hua JIN
;
Min-Ke LIU
;
Shuang-Fang LIU
;
Bi-Shi LING
;
Shang-Wen QI
;
Xue-Li MA
Author Information
1. 甘肃中医药大学中医临床学院 甘肃兰州 730000
- Keywords:
hypertension;
osteoporosis;
intestinal flora
- From:
The Chinese Journal of Clinical Pharmacology
2024;40(3):449-453
- CountryChina
- Language:Chinese
-
Abstract:
Hypertension and osteoporosis(OP)are common diseases in middle-aged and elderly people,and the number of patients with both diseases has gradually increased in recent years.Because the onset of the disease is hidden,it is easy to cause fractures and serious complications of heart,brain and kidney in the later stage,which not only seriously damages the quality of life of patients,but also increases the difficulty of clinical treatment.Therefore,it is particularly necessary to strengthen the research on this disease.More and more studies have found that the disorder of intestinal flora will lead to the occurrence of OP,while the intestinal flora of patients with hypertension is obviously out of balance.Therefore,this paper thinks that intestinal flora may be the key influencing factor of hypertension complicated with OP,and the imbalance of intestinal flora will lead to the imbalance of short-chain fatty acid metabolism,immune inflammatory reaction and increased sympathetic nerve activity,thus causing the imbalance of bone homeostasis and promoting the occurrence of OP.Therefore,it is suggested that regulating intestinal flora may be a new way to intervene hypertension complicated with OP.
