Progress in the application of antibody drugs in the treatment of diabetes
10.13699/j.cnki.1001-6821.2019.08.025
- VernacularTitle:抗体药物在糖尿病治疗应用的研究进展
- Author:
Qing-Mei ZHENG
1
;
Ya-Duan WANG
;
Shuang-Yu TAN
;
Xiao-Le CHEN
;
Nan-Wen ZHANG
;
Ju-Hua YANG
Author Information
1. 福建医科大学 药学院
- Keywords:
antibody drugs;
T cell;
B lymphocyte;
glucagon receptor;
vascular endothelial growth factor
- From:
The Chinese Journal of Clinical Pharmacology
2019;35(8):812-815
- CountryChina
- Language:Chinese
-
Abstract:
Diabetes,a chronic metabolic disease with hyperglycemia,has a high incidence in the modern time that put many patient families into troubles. At present,insulin or oral hypoglycemic agents are used to treat diabetes,though several side effects such as hypoglycemia and various complications mainly caused by these drugs. Antibody with high selectivity and high therapeutic index is employed in many disease treatments. In this paper,the recent study of different antibodies against certain targets of T cells,B lymphocytes,glucagon receptors and vascular endothelial growth factor are involved,which could supply new insight into the treatment of diabetes.