Research status of microRNA mediated drug regulation of transporter and metabolizing enzymes
10.13699/j.cnki.1001-6821.2018.20.020
- VernacularTitle:微小RNA介导的药物对转运体调控作用的研究进展
- Author:
Wei DING
1
;
Yu-Qing XIONG
Author Information
1. 南昌大学 临床药理研究所
- Keywords:
microRNA;
drug transporter;
regulation
- From:
The Chinese Journal of Clinical Pharmacology
2018;34(20):2465-2468
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNAs,a family of endogenous non -coding RNAs, are known for their critical role in regulating the expression of target genes through complementary binding to the 3'non-coding region of the target gene mRNA.Drugs indirectly affect drug metabolism by regulating the expression of microRNAs that affect transporters .This article systemati-cally described the research progress and mechanism of microRNA media-ted drug regulation of transporters .
