Analysis of common etiology of fatty liver in recent ten years in China
10.13699/j.cnki.1001-6821.2018.20.015
- VernacularTitle:中国近10年脂肪肝常见病因的分析
- Author:
Yong-Yong ZHANG
1
;
San-Qiang LI
;
Ying SONG
;
Shan-Long WANG
;
Wen-Feng ZHU
;
Xiao-Gai SONG
;
Chen-Yang MAI
;
Zhang-Yu TIAN
;
Fei-Yu BAI
Author Information
1. 河南科技大学 医学院 肝损伤与修复分子医学重点实验室
- Keywords:
fatty liver;
etiology;
Meta-analysis
- From:
The Chinese Journal of Clinical Pharmacology
2018;34(20):2445-2448
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the common causes of fatty liver in Chinese adults.Methods The CNKI, WANFANG database and VIP database were searched by computer , and the etiology of fatty liver was published from January 2008 to December 2017.Meta-analysis of pre-valence, influencing factors, and blood biochemical indicators were per-formed using R software and Stata software .Results Twenty-four stu-dies were finally included,with a total of 49,275 cases.Meta-analysis showed that the prevalence of fatty liver in the population were : total prevalence 19.31%, male prevalence 26.44%, female prevalence 15.31%.The prevalence rates at different ages were :＜30 years old 13.20%, 31-40 years old 16.73%, 41-50 years old 20.98%, 51-60 years old 21.85%,＞60 years old 17.46%.The risk ratio of influen-cing factors in patients with fatty liver compared with normal population was: high cholesterol 2.03, high triglyceride 3.02, aspartate transaminas increased 3.70, alanine transaminase increased 4.55, hyperglycemia 2.54, obesity 10.73 , greasy food 3.93, alcohol consumption 2.85, hy-pertension 2.06, quality index fat 2.52.The differences in mean blood biochemical results between patients with and without fatty liver were as follows: total cholestero 1.23,triglyceride 1.18,high-density lipoprotein -0.55,low-density lipoprotein 0.28, aspartate transaminase 1.09, alanine transaminase 1.45,total bilirubin 1.09, fasting blood glucose 1.16.Conclusion The preva-lence of fatty liver in Chinese men is higher than that in females ; common factors are high cholesterol , high triglycerides, elevated aspartate transaminase, elevated alanine transaminase, hyperglycemia, obesity, greasy food, hypertension, body mass index; patients with fatty liver fatty biochemical indicators than the normal population were abnormal.
