Effect of clostridium butyricum tablets combined with conventional therapy on the levels of cholinesterase and albumin in patients with liver cirrhosis
10.13699/j.cnki.1001-6821.2018.20.001
- VernacularTitle:常规方法联用络酸梭菌活菌片对肝硬化患者血浆胆碱酯酶与白蛋白水平的影响
- Author:
Hui FAN
1
;
Nai-Kuo ZHAO
;
Zheng-An ZHANG
;
Qing-Jun HU
;
Xin-Jun HU
Author Information
1. 焦作市人民医院 消化一区
- Keywords:
liver cirrhosis;
Clostridium butyricum tablets;
cholinesterase;
albumin
- From:
The Chinese Journal of Clinical Pharmacology
2018;34(20):2395-2397
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of Clostridium butyricum tablets combined with conventional therapy on the cholinesterase levels and albumin ( ALB) levels in patients with liver cirrhosis.Methods The 236 patients with liver cirrhosis from October 2016 to February 2018 in the Department of Gastroenterology of our hospital were selected as the study subjects.The patients were divided into the treatment group and the control group.The patients in the treatment group were given 2 g Clostridium butyricum tablets orally ,on the basis of general symptomatic treatment,3 times per day for two weeks ;the patients in the control group were stan-dard treatment.The plasma cholinesterase , ALB levels were determined by automatic analyzer.Results The cholinesterase levels in the control group and the treatment group were ( 2.87 ±1.82 ), (7.94 ±2.45) U· L-1, respectively; the ALB levels in the 2 groups were (34.02 ±3.26),(47.63 ±4.05) g· L-1,respectively;comparison between the two groups , the difference was significant ( all P ＜0.05 ) . Conclusion Clostridium butyricum tablets can significantly increase plasma cholinesterase and ALB levels in patients with liver cirrhosis .
