Bibliometric analysis of the adverse drug reactions of rivaroxaban
10.13699/j.cnki.1001-6821.2018.19.030
- VernacularTitle:利伐沙班药物不良反应的文献计量分析
- Author:
Xiao-Ming DU
1
;
Mei-Ting ZHU
;
Li-Mei ZHAO
Author Information
1. 中国医科大学 附属盛京医院 药学部
- Keywords:
rivaroxaban;
drug adverse reaction;
document analysis
- From:
The Chinese Journal of Clinical Pharmacology
2018;34(19):2348-2351
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the general law of adverse drug reac-tions (ADRs) in rivaroxaban.Methods Based on the domestic litera-ture retrieved from China hospital knowledge database ( CNKD), VIP network,VIP, Wanfang database ,and PubMed from 1 January 2008 to 11 January 2018, ADRs caused by rivaroxaban were summarized and statis-tically analyzed.Results The study collected 78 literature and 40589 cases of the ADRs of rivaroxaban.Rivaroxaban caused various complicat-ed ADRs and clinical manifestations , which on the top of lists were re-spiratory system disorders and gastrointestinal disorders .Conclusion Adverse drug reactions monitoring of rivaroxaban should be strengthened to ensure its safety and medication.