Current status of intestinal flora as a new target for treatment of cardiovascular diseases
10.13699/j.cnki.1001-6821.2018.07.048
- VernacularTitle:肠道菌群作为心血管疾病治疗新靶点的研究现状
- Author:
Min LI
1
;
Ming L(U)
;
Jing-Yu NI
;
Guan-Wei FAN
Author Information
1. 天津中医药大学第一附属医院医学实验中心
- Keywords:
intestinal microbiota;
cardiovascular disease;
flora imbalance;
trimethylamine N-oxide
- From:
The Chinese Journal of Clinical Pharmacology
2018;34(7):903-905
- CountryChina
- Language:Chinese
-
Abstract:
Intestine,the body's largest digestive and immune organ,always affects the occurrence and development of cardiovascular disease process.Especially the trimethylamine N-oxide as one of the metabolic derivatives produced by intestinal microbiota,can increase the risk of atherosclerosis and promote cardiovascular diseases such as chronic heart failure.Therefore,changing the level of trimethylamine N-oxide in the circulation by taking different measures to intervene the structure,composition and metabolic activity of intestinal flora can affect the occurrence and development of the disease.Thus,the intestinal flora is recognized as a new target for the treatment of cardiovascular diseases.
