Oxazolidinone antibacterial agents and Gram-positive bacteria treatment
10.13699/j.cnki.1001-6821.2018.07.047
- VernacularTitle:恶唑烷酮类抗菌药物与革兰氏阳性菌治疗的研究现状
- Author:
Xi-Wei JI
1
;
Xiang-Rui MENG
;
Yuan L(U)
;
Chi-Shing CHO
Author Information
1. 北京大学第一医院临床药理研究
- Keywords:
oxazolidinones;
Gram-positive bacteria;
safety;
antibiotic resistance;
structural modification
- From:
The Chinese Journal of Clinical Pharmacology
2018;34(7):898-902
- CountryChina
- Language:Chinese
-
Abstract:
Oxazolidinones are a potent class of synthetic antimicrobial agents with activity mainly against Gram-positive strains.In this review,we summarize the mechanism of action and resistance,as well as the safety from clinical experience of oxazolidinones.The structural modifications and structure-activity relationships of oxazolidinones derivatives will also be presented.
