Influence of intramuscular injection of vitamin D2 on serum 25-hydroxyvitamin D in aged women
10.13699/j.cnki.1001-6821.2018.06.009
- VernacularTitle:维生素D2对高龄女性血清25-羟基维生素D的影响
- Author:
Qi-Gang YANG
1
;
Su-Feng QIAN
;
Ping-Da BIAN
;
Zhang-Xuan SHOU
;
Jin-Ping CHEN
Author Information
1. 浙江省人民医院、杭州医学院附属人民医院望江山院区消化科
- Keywords:
vitamin D;
calcium;
aged women
- From:
The Chinese Journal of Clinical Pharmacology
2018;34(6):640-642
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the influence of intramuscular injection of vitamin D2 on serum 25-hydroxyvitamin D in aged women.Methods A total of 40 aged women were randomly divided into treatment group and control group,each group 20 patients.Patients in treatment group were given vitamin D2 injection 6.0 × 105 U every month,intramuscular injection,for 3 months.Control group was given sunshine treatment The levels of serum 25-hydroxyvitamin D and calcium were evaluated and compared before treatment and after 8 months treatment.Results After 3 months treatment,serum 25-hydroxyvitamin D in treatment group and control group were (19.76 ± 3.28),(16.37 ± 3.01)ng · mL-1,with significant difference (P ＜ 0.01),and the levels of serum 25-hydroxyvitamin D in other times had no significant difference (all P ＞ 0.05).There was no significant difference in serum calcium between treatment and control group during 9 months (all P ＞ 0.05).Conclusion Vitamin D2 injection could be used to increase serum 25-hydroxyvitamin D level,and it had no effect on serum calcium.
