Pharmaceutical care for a child with concurrent cryptococcal meningitis complicated by nephrotic syndrome
10.13699/j.cnki.1001-6821.2018.03.045
- VernacularTitle:新型隐球菌性脑膜炎合并肾病综合征患儿的药学监护
- Author:
Xian-Ting XIE
1
;
Chao-Yang CHEN
;
Hai-Sheng YOU
;
Zong-Yan LIU
;
Ying ZHOU
;
Yi-Min CUI
Author Information
1. 北京大学第一医院药剂科
- Keywords:
concurrent cryptococcal meningitis;
nephrotic syndrome;
amphotericin B;
fluconazole
- From:
The Chinese Journal of Clinical Pharmacology
2018;34(3):340-342
- CountryChina
- Language:Chinese
-
Abstract:
Objective To provide medication references for children with new cryptococcal meningitis with nephrotic syndrome.Methods The clinical pharmacists participate in formulation of treatment plans,and monitor the curative effect of anti-infective treatment,intracranial pressure depressing,and nephrotic syndrome treatment during therapy.They should adjust the usage and dosage of nephrotoxic drugs by monitoring patients' renal function and electrolyte condition,and propose individualized drug administration advices according to patients' conditions and adverse reactions.Results and conclusion The anti-cryptococcus treatment was effective,the nephrotic syndrome was stable,the symptoms of intracranial hypertension were improved,hypokalemia and hypomagnesemia were corrected,and the renal function impairment was not aggravated.The clinical pharmacists' combining of pharmaceutical theory with clinical practice received clinicians'recognition,and promoted children's medication safety and rational drug use.