Research progress of the bidirectional regulation of reactive oxygen species on tumor
10.13699/j.cnki.1001-6821.2017.19.042
- VernacularTitle:活性氧对肿瘤双向调节作用的研究进展
- Author:
Li-Li LI
1
;
Fang-Rui DONG
;
Shi-Lei ZANG
;
Lin-Quan ZANG
Author Information
1. 广东药科大学药理系
- Keywords:
reactive oxygen species;
tumor;
apoptosis;
mechanism
- From:
The Chinese Journal of Clinical Pharmacology
2017;33(19):1993-1996
- CountryChina
- Language:Chinese
-
Abstract:
Reactive oxygen species (ROS),produced by the body cause the normal state turning into cancerous state,is one of the main reasons of malignant tumor.In addition,ROS is one of the main therapeutic mechanisms of most chemotherapy and radiotherapy for malignant tumor.This bidirectional regulation is achieved through different signaling pathways and mechanisms.Exogenous ROS during anti-cancer treatment,as appropriate,could contribute to the research and development of new anti cancer agents.In this paper,we summarize the carcinogenic/anticancer effect of ROS through the different mechanism,providing new ideas for prevention,control and the treatment of malignant tumors.
