Analysis of off-indication use of voriconazole
10.13699/j.cnki.1001-6821.2017.17.027
- VernacularTitle:伏立康唑临床超说明书的应用分析
- Author:
Shu-Yao LIANG
1
;
Ken CHEN
;
Suo-Di ZHAI
Author Information
1. 北京大学第三医院药剂科
- Keywords:
voriconazole;
off-indication
- From:
The Chinese Journal of Clinical Pharmacology
2017;33(17):1706-1709
- CountryChina
- Language:Chinese
-
Abstract:
Objective To provide evidence for the off-indication use of voriconazole.Methods PubMed,EmBase,the CochraneLibrary and three Chinese databases (CNKI,SinoMed and WangFang) were searched through January 2016.The indications,pathogens,route of administration,cure rate and type of study were inclu-ded in the statistical analysis.All thestudies about the off-indication use of voriconazole were included,according to the established criteria.Results Thirty-nine case reports and case series involving the off-indication use and research advance of voriconazole on ocular infections,skin and soft tissue infections,bone and joint infections,abdominal infections,cardiac infection,and histoplasmosiswere included in the review.Conclusion We provided support for the treatment of fungal infections in rare sites with a low incidence rate and no clear antifungal treatment regimen.
