Analysis of uses drugs in inpatients with hypertesive disorders of pregnancy
10.13699/j.cnki.1001-6821.2017.16.022
- VernacularTitle:妊娠期高血压疾病住院患者用药分析
- Author:
Chun-Mei YAN
1
;
Wen ZOU
;
Fan-Zhen HONG
;
Yong-Ping XU
;
Hong-Ying JIA
;
Huan-Di LIU
;
Ying-Hui ZHANG
;
Juan XIAO
;
Yuan ZHANG
Author Information
1. 山东大学第二医院产科
- Keywords:
hypertensive disorders of pregnancy;
inpatients;
drug analysis;
evidence-based pharmacy
- From:
The Chinese Journal of Clinical Pharmacology
2017;33(16):1590-1593
- CountryChina
- Language:Chinese
-
Abstract:
Objective To retrospectively investigate the drug use of the patients with hypertensive disorders of pregnancy (HDP) so as to evaluate the rationality of the drug use among these patients.Methods The information of the inpatients with HDP as the initial diagnosis in this hos pital from January 2011 to June 2015 was collected,including the patientcharacteristics,drug use,costs,etc.The data was analyzed by the SPSS 22.0 software.Results In sum,974 HDP cases were included,among which severe preeclampsia is the main component with 38.81％ (378/ 974 cases).Drug analysis showed that there were four types of anti-hypertensive drugs,three preeclampsia-prophylaxis drugs,three sedatives,one diuretic,one anti-hypoalbuminemia drug,and one Chinese medication.The patients were divided into subgroups according to HDP classification and there was subtle difference among the subgroups.The top ten drugs according to the use frequency were vitamin C,vitamin E,nifedipine,ligustrazine,magnesium sulfate,nifediping sustained-release tablets,albumin,diazepam,urapidil,and furosemide.Conclusion The HDP treatments were mainly composed by the preeclampsia prophylaxis and the anti-hypertension.Ligustrazine acted as an adjunctive treatment.The treatments above were consistent with the guidelines,which was rational.But the use of Vitamin C and E was controversial.
