Study on anti-fatigue and hypoxia tolerance function of Jasmine leaves' water extract in mice
10.13699/j.cnki.1001-6821.2017.16.017
- VernacularTitle:茉莉花叶水提液影响小鼠抗疲劳及耐缺氧能力的研究
- Author:
Xun-Jie LIANG
1
;
Xiao-Xia HUANG
;
Mian LU
;
Yuan-Sheng BI
;
Ya-Ting TANG
;
Meng-Yao LIN
;
Suo-Yi HUANG
Author Information
1. 右江民族医学院临床医学院
- Keywords:
Jasmine leaves'water extract;
anti-fatigue;
hypoxia tolerance;
liver weight coefficient;
swimming
- From:
The Chinese Journal of Clinical Pharmacology
2017;33(16):1575-1577
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study on the anti-fatigue and hypoxia tolerance function of Jasmine leaves' water extract in mice.Methods Forty-eight normal male mice were averagely selected and divided into four groups by weight:blank control group,low concentration experimental group,medium concentration experimental group and high concentration experimental group.Jasmine leaves' water extract of different concentrations (0,200,400,600 mg· mL-1 respectively for the four groups) was given into the mice's stomach for a continuous 16 days,each mice was given 10 mL · kg-1 a day.Burdened swimming test and hypoxia tolerance test were conducted in the mice to determine their swimming time and death time.The liver weight coefficient was calculated.Results The burdened swimming time:Compared with blank control group 9.27 min,that were 9.41,15.42,10.63 min in low,medium,high concentrations experimental groups respectively while medium experimental group had significantly (P ＜ 0.05).The hypoxia tolerance time:Compared with blank control group (47.56 ± 5.61)min,that were (56.24 ± 10.99),(47.20 ± 4.51),(53.44 ± 7.56) min in low,medium,high concentrations experimental groups respectively while low experimental group had significantly (P ＜ 0.01).The liver weight coefficient:Compared with blank control group (4.84 ± 0.29) × 10-2,that were (5.20 ± 0.72) × 10-2,(5.43 ±0.39) × 10-2,(5.42 ± 0.57) × 10-2 in low,medium,high concentrations experimental groups respectively while medium,high experimental groups had significantly(all P ＜ 0.01).Conclusion Jasmine leaves' water extract is proved to have anti-fatigue and hypoxia tolerance function in mice.
