Anesthetic efficacy of lidocaine injection combined with ropivacaine injection in the treatment of digital replantation
10.13699/j.cnki.1001-6821.2017.12.015
- VernacularTitle:利多卡因注射液联合罗哌卡因注射液对断指再植术的麻醉疗效
- Author:
Chao-Qun KE
1
;
Zhi-Bin HUANG
;
Chang-Ming TANG
;
Hui-Qing LIN
;
Shou-He WU
Author Information
1. 福建省立医院麻醉科
- Keywords:
ropivacaine injection;
lidocaine injection;
digital replantation;
anesthesia efficacy;
safety
- From:
The Chinese Journal of Clinical Pharmacology
2017;33(12):1123-1126
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the anesthetic efficacy and safety of lidocaine injection combined with ropivacaine injection in the treatment of digital replantation.Methods Seventy-two patients underwent replantation were randomly divided into control group (n =36 cases) and treatment group(n =36 cases).Control group was given ropivacaine injection 10 mL with upper limb vein injection.Treatment group received lidocaine injection 10 mL with upper limb vein injection,on the basis of control group.The anesthetic effect,C reactive protein(CRP) and adverse drug reactions were compared between the two groups.Results The proportion of anesthesia effect of grade Ⅰ in treatment and control groups were 97.22％ (35/36 cases) and 83.33％ (30/36 cases) with significant difference(P ＜0.05).After operation 1,3 d,the levels of CRP in treatment group were(7.25 ± 1.07),(7.14 ± 0.96) mg · L-1,which in control group were(8.12 ± 1.18),(7.90 ± 1.01) mg · L-1 with significant difference (P ＜ 0.05).The main adverse drug reactions in treatment group were based on limb movement and skin flushing,which in control group were based on limb,skin flushing and skin itching.The incidences of adverse drug reactions in treatment and control groups were 5.56％ and 22.22％ with significant difference (P ＜ 0.05).Conclusion Lidocaine injection combined with ropivacaine injection has a definitive anesthetic efficacy and safety in the treatment of digital replantation.
