Progress on the effects of melatonin on the activity of stem cells in the micro environment of injury
10.13699/j.cnki.1001-6821.2017.11.030
- VernacularTitle:褪黑激素影响损伤微环境中干细胞活性的研究进展
- Author:
Li PAN
1
;
Zi-Qiang ZHANG
;
Yu-Mei LIU
;
Ke SHI
;
Wen-Jie YANG
Author Information
1. 河南科技大学动物科技学院
- Keywords:
melatonin;
stem cell;
survival;
microenvironment
- From:
The Chinese Journal of Clinical Pharmacology
2017;33(11):1058-1060
- CountryChina
- Language:Chinese
-
Abstract:
In recent years,studies have shown that stem cells can be used to repair tissue and organ damage,but the lowly survival rate of stem cell transplantation has become a disadvantage of clinical application.Melatonin is a kind of neuroendocrine hormone that has many physiological functions,and an increasing number of researches have shown that it not only can affect stem cell proliferation and differentiation,but also can significantly improve the survival rate of stem cell transplantation.Therefore,in order to provide reference resources for repairing tissue and organ damage by using melatonin and stem cell,the effects of melatonin on the activity of stem cells in the microenvironment of injury were reviewed.