Study on effects of different infusion sets on absorption of butylphthalide sodium chloride injection
10.13699/j.cnki.1001-6821.2017.07.017
- VernacularTitle:不同材质输液器对丁苯酞氯化钠注射液的吸附性考察
- Author:
Yuan-Yuan XIAO
1
;
Chun-Hua ZHOU
;
De-Qiang LI
;
Meng XU
Author Information
1. 大城县医院创伤科
- Keywords:
butylphthalide sodium chloride injection;
packaged infusion set;
polyvinyl chloride infusion set;
polyolefin thermoplastic elastomer infusion set;
adsorbability
- From:
The Chinese Journal of Clinical Pharmacology
2017;33(7):634-637
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the absorbability of the packaged infusion sets of butylphthalide,polyvinyl chloride (PVC) or polyolefin thermoplastic elastomer (TPE) infusion sets on butylphthalide for providing clinical reference in the choice of infusion sets.Methods Solution of butylphthalide was prepared as peractual concentration needed by the clinic,and dripped through PVC,TPE and packaged infusion sets respectively.The dripped solutions at different time points were collected and determined by HPLC,the contents were compared with that at 0 min.Results In the end of infusion,the adsorption rate of PVC,TPE and packaged infusion sets on butylphthalide were 0.47％,32.48％,9.62％,respectively.In addition,the absorbability of the infusion sets frown different manfacturers on butylphthalide had no significant differece.Conclusion The infusion sets of PVC had a serious absorption on butylphthalide.
