Progress in continuous versus intermittent infusion of β-lactam antibiotics
10.13699/j.cnki.1001-6821.2017.06.024
- VernacularTitle:β内酰胺类抗生素不同输注方法研究进展
- Author:
Ming-Ming RUAN
1
;
Hang SHA
;
Xu-Hong YU
Author Information
1. 南方医科大学研究生学院
- Keywords:
β-lactam antibiotics;
continuous infusion;
intermittent infusion
- From:
The Chinese Journal of Clinical Pharmacology
2017;33(6):570-573
- CountryChina
- Language:Chinese
-
Abstract:
Recent clinical research shows that a prolonged infusion administration strategy of β-lactam antibiotics compared with intermittent infusion,may improve microbiologic and clinical cure,especially when pathogens demonstrate higher minimum inhibitory concentrations (MIC).This article reviews β-lactam pharmacodynamic background and advantages,clinical benefits and risks,clinical efficacy and potential drawbacks of prolonged infusion β-lactam antibiotics.
