Clinical and economic outcomes associated with Beers criteria of potentially inappropriate medication use: A systematic review
10.13699/j.cnki.1001-6821.2017.06.018
- VernacularTitle:Beers标准评价老年人潜在不适当用药临床经济结局的系统评价
- Author:
Jian-Ping ZHANG
1
;
Dai-Yun ZHONG
;
Li-Qing LU
;
Jin YUAN
;
Jian LI
Author Information
1. 暨南大学药学院
- Keywords:
Beers criteria;
elderly;
potentially inappropriate medication;
outcome research;
systematic review
- From:
The Chinese Journal of Clinical Pharmacology
2017;33(6):547-550
- CountryChina
- Language:Chinese
-
Abstract:
Objective To examine clinical and economic outcomes associated with Beers criteria (2003 and 2012 version) of potentiallyinappropriate medication(PIM) use.Methods A systematic literature search about impact of 2003 and 2012 Beers criteria published from 2003 to 2016 was carried out in following databases:PubMed,Cochrane library,CNKI and CBM.The studies were screened according to the pre-designed in clusion and exclusion criteria,and were assessed risk of bias using Newcastle-Ottawa scale (NOS).Data were extractedto performmeta-analysis and descriptive analysis.Results A total of 23 studies were included in our systematic review.All the study scores were more than 6 stars.The results of analysis suggested that,patients with PIM identified by Beers criteria had higher incidence of hospitalization [OR =1.47,95％ CI (1.14,1.89),P＜0.01],ADR[OR =1.74,95％ CI(1.23,2.47),P ＜0.01],emergency department visit(ED visit) [OR =1.69,95％ CI (1.21,2.37),P ＜ 0.01] and cost compared with non-PIM patient,but there was no significantly different in mortality and health-related quality of life (HRQOL).Conclusion The application of Beers criteria can reduce hospitalization,ED visit and ADR.
