Repeated elevation of carcinoembryonic antigen induced by alendronate sodium in an elder osteoporosis woman
10.13699/j.cnki.1001-6821.2017.05.021
- VernacularTitle:1例阿仑膦酸钠致老年女性骨质疏松患者的癌胚抗原反复增高
- Author:
Zhang-Xuan SHOU
1
;
Ping-Da BIAN
;
Xue JIN
Author Information
1. 浙江省人民医院、杭州医学院附属人民医院药学部
- Keywords:
alendronate sodium;
carcinoembryonic antigen;
osteoporosis
- From:
The Chinese Journal of Clinical Pharmacology
2017;33(5):461-462
- CountryChina
- Language:Chinese
-
Abstract:
Objective One case of repeated elevation of carcinoembryonic antigen (CEA) induced by alendronate sodium in an elder osteoporosis woman was introduced to draw physicians'attention.Methods One elderly women with osteoporosis was treated with oral alendronate sodium 70 mg,once a week.The serum CEA was detected at an regular interval.The relationship between CEA elevation and alendronate sodium therapy was evaluated with Naranjo's assessment scale.Results and conclusion The serum level of CEA was repeatedly observed to gradually increase several weeks after treatment,while gradually decline after discontinuing the medication.The elevation of CEA took placed in a sequential manner in relation to the administration of alendronate sodium.Naranjo's assessment gave a total score of 8 points,indicating that CEA may be associated with the use of alendronate sodium.
