Reinforcement precision medication in clinical pharmacy education
10.13699/j.cnki.1001-6821.2017.04.022
- VernacularTitle:对临床药学专业学生应加强精准用药教育
- Author:
Xin-Gang LI
1
;
Ke-Fu YU
;
Ji-Ping HUO
;
Yue-Ting ZHU
;
Bin ZHU
;
Zhi-Gang ZHAO
Author Information
1. 首都医科大学附属北京天坛医院药学部
- Keywords:
clinical pharmacy;
precision medicine;
genetic factor;
non-genetic factor
- From:
The Chinese Journal of Clinical Pharmacology
2017;33(4):369-371
- CountryChina
- Language:Chinese
-
Abstract:
Precision medicine is one of the most important development in the future.In our study,the main contents of precision medication education were presented,and we aimed to provide a reference for clinical pharmacy educators.There are many factors affecting drug efficacy,and the factors could be divided into two categories of genetic and non-genetic factors.Genetic factors include genetic mutations,epigenetic modification,gene expression,miRNA etc.and non-genetic factors can be subdivided into drug-drug interaction,physiological factor,pathological factor,and other factors.Multiple knowledge was related to Precision medicine,such as pharmacogenetics,genetic testing,bioinformatics pharmacogenetics,therapeutic drug monitoring,pharmacometrics and so on.Take warfarin for example,we explained each factor effecting warfarin anticoagulant therapy.The commonly used databases for precise medication were also summarized.Related basic knowledge is the basis of precision medicine.In clinic,specific drug should be analyzed specifically.In order to constantly update knowledge,we should learn to use the common databases.
