Study on the drug sensitivity test of respiratory Pseudomonas aeruginosa in vitro
10.13699/j.cnki.1001-6821.2016.13.012
- VernacularTitle:呼吸道铜绿假单胞菌体外药敏试验研究
- Author:
Xiao-Hua ZHANG
1
;
Zuo-Ming YANG
;
Chang-Ling FAN
;
Mei-Feng LI
Author Information
1. 儋州市农垦那大医院 检验科
- Keywords:
respiratory tract;
Pseudomonas aeruginosa;
drug sensitivity test;
drug resistance
- From:
The Chinese Journal of Clinical Pharmacology
2016;32(13):1192-1193,1213
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the drug sensitivity of respiratory Pseudomonas aeruginosa.Methods Drug sensitivity test of 481 isolated strains of Pseudomonas aeruginosa was performed with agar dilution method in vitro. The susceptibility , drug resistance and intermediary rate of strains of Pseudomonas aeruginosa and those insensitive to imipenem were determined according to the minimal inhibitory concentration ( MIC ) . Results Pseudomonas aeruginosa in respiratory had the lowest resistance rate to amikacin (12.06%), followed by imipenem with 13.93%resis-tance and had the highest resistance to sulfamethoxazole /trimethoprim ( SMZ/TMP) which was 99.79%.96 strains insensitive to imipenem had the lowest resistance to amikacin ( 16.67%) , but to SMZ/TMP they had highest resistance rate of 98.96%.Conclusion According to drug re-sistance status of Pseudomonas aeruginosa bacteria in our hospital , the empirical treatment with imipenem , ciprofloxacin and other antimicrobial agents was recommended , and based on this , the combined use of amika-cin is expected to achieve better control effect .
