Bibliometric analysis of research papers on mutant prevention concentration
10.13699/j.cnki.1001-6821.2016.12.025
- VernacularTitle:防耐药突变浓度理论文献计量的近况分析
- Author:
Hui NIU
1
;
Bei-Bei MIAO
;
Yan YANG
;
Bei-Bei LIANG
;
Nan BAI
;
Ming-Jing TANG
;
Rui WANG
;
Jin WANG
Author Information
1. 解放军总医院 医务部转化医学中心 药物临床试验中心
- Keywords:
mutant prevention concentration;
mutant selection window;
bibliometric analysis;
literature research
- From:
The Chinese Journal of Clinical Pharmacology
2016;32(12):1138-1141
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the recent advance on mutant preven-tion concentration ( MPC) over the past years with bibliometric approach for advanced research of MPC.Methods Literatures were searched from PubMed, EMbase, Science Citation Index, CNKI and Wanfang from 1999 to Oct.2015.EndNote X7 was used to sort these articles and the bibliometric analysis was carried out in respect of published years , first authors, published journals, cited frequency and contents, etc.Results A total of 442 articles were collected in our research , including 266 English articles and 176 Chinese papers.The number of articles about MPC published in 2010 was the most.Antimicrob Agents Chemother was the ranked the first place in all of journals for MPC published pa-pers.From the aspect of content , most of the articles still focused on the in vitro and animal study to investigate the relationship between pharma-cokinetic/pharmacodynamics ( PK/PD ) parameters on the basis of the MPC.However , the animal models and in vitro PD models were increa-sing and their aims were tend to clinical application these years.Conclusion With the passage of time , researches of MPC deepened gradually , and also played an important role for clinical.
