Candida famata Infection Presenting as an Erosive Patch on the Sole of an Immunocompetent Patient.
- Author:
Byeong Jin PARK
1
;
Hyun Seok CHOI
;
Hyung Kwon PARK
;
Young Gyun KIM
;
Joung Soo KIM
;
Hee Joon YU
Author Information
1. Department of Dermatology, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Korea. yuhjoon@hanyang.ac.kr
- Publication Type:Case Report
- Keywords:
Candida famata;
Cutaneous candidiasis
- MeSH:
Biopsy;
Candida*;
Candidiasis, Cutaneous;
Coloring Agents;
Epidermis;
Female;
Fungi;
Humans;
Hyperpigmentation;
Hyphae;
Itraconazole;
Methenamine;
Skin;
Spores;
Yeasts
- From:Korean Journal of Dermatology
2017;55(7):449-453
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Candida famata previously called Torulopsis famata or Debaryomyces hansenii, is usually found in natural substrates. It was earlier considered nonpathogenic in humans; however, a number of clinical cases of human infection have been reported showing isolation of this yeast. Dermatologic literature contains only a few reports regarding cutaneous infection caused by Candida famata. An 18-year old woman presented with a 4-month history of a 4.0×3.0 cm sized erythematous erosive patch on her left sole. A skin biopsy revealed numerous spores and hyphae in the epidermis. Histopathological specimens showed positive findings using the Periodic acid-Schiff and Gomori methenamine silver stains but negative findings using acid-fast bacilli stain. Cultures from skin scrapings yielded numerous colonies. Identification of the fungus was processed up to species level using VITEK 2 (bioMérieux, Inc. Hazelwood, MO, USA), and Candida famata was isolated. She was administered itraconazole at a dose of 200 mg once daily, and following 5 weeks of therapy, the erosive lesion was noted to have completely healed with postinflammatory hyperpigmentation.
