Leser-Trelat Sign Associated with Malignant Melanoma.
- Author:
Dong Yeup LEE
1
;
Jong Heon BAEK
;
Dong Joo KIM
;
Myoung Shin KIM
;
Un Ha LEE
;
Hyun Su PARK
Author Information
1. Department of Dermatology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Leser-Trelat sign;
Melanoma;
Seborrheic keratosis
- MeSH:
Adenocarcinoma;
Gastrointestinal Tract;
Hematuria;
Humans;
Keratosis, Seborrheic;
Lymphoproliferative Disorders;
Male;
Melanoma*;
Middle Aged;
Penis;
Skin Diseases
- From:Korean Journal of Dermatology
2014;52(12):895-899
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Leser-Trelat sign is a rare paraneoplastic dermatosis that is characterized by the eruptive and rapid development of multiple seborrheic keratosis that coincides with an internal malignancy. Eruptive seborrheic keratosis can be pruritic and appear in a "Christmas-tree pattern." This sign occurs in association with a number of cancers, such as adenocarcinoma of the gastrointestinal tract and various lymphoproliferative disorders. However, Leser-Trelat sign associated with a malignant melanoma is very rare. A 58-year-old male patient presented with an asymptomatic black mass on the penile orifice and patch on the glans penis. He complained of gross hematuria. At the same time, he developed asymptomatic multiple brown papules and plaques on the back. The histopathologic findings of the glans and back lesions were consistent with malignant melanoma and seborrheic keratosis, respectively. Here, we describe a rare case of Leser-Trelat sign associated with malignant melanoma.
