Clinical trial of ganglioside combined with ginkgo dipyridamolum in the treatment of craniocerebral injury
10.13699/j.cnki.1001-6821.2016.12.006
- VernacularTitle:神经节苷脂联合银杏达莫对颅脑损伤患者的临床研究
- Author:
Sheng WANG
1
;
Chao-Ping WANG
;
Tai-Dong CHEN
Author Information
1. 海南省琼海市人民医院 神经外科
- Keywords:
ganglioside;
ginkgo dipyidamolum;
craniocerebral injury
- From:
The Chinese Journal of Clinical Pharmacology
2016;32(12):1075-1077
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical effect of ganglioside com-bined with ginkgo dipyridamolum in the treatment of craniocerebral inju-ry.Methods Sixty-four traumatic brain injury patients were randomly divided into treatment group and control group , 32 cases in each group.Control group was intravenously dripped ganglioside 20 mL, two times a day.Treatment group was intravenously given the injection of ginkgo dipyridamolum 10 mL, once a day , on the basis of control group.All pa-tients were treated for 1 month.Clinical effect , activity of daily living ( ADL) score, the degree of neurological deficit and the incidence of ad-verse drug reactions were observed.Results After treatment , the clini-cal efficacy of treatment group was 96.87%, significantly higher than 78.13%in control group ( P<0.05 ).After treatment , the ADL scores of two groups were significantly higher than those before treatment ( P<0.05 ).The neurological deficit score in treatment group was statisti-cally lower than that before treatment and control group ( P <0.05 ).There were no adverse drug reactions in two groups during the treatment.Conclusion The clinical effect of ganglioside combined with ginkgo dipyridamolum in the treatment of craniocerebral injury was better than that of ganglioside , which can improve the ability of daily life and the quality of life of patients.
