Research progress of establishment and validation of warfarin dose prediction model
10.13699/j.cnki.1001-6821.2016.08.031
- VernacularTitle:华法林剂量预测模型的建立与验证的研究进展
- Author:
Xue SUN
1
;
Wan-Le MA
;
Wen-Yu LIU
;
Guo-Ping YANG
Author Information
1. 中南大学药学院
- Keywords:
warfarin;
anticoagulation;
gene;
model
- From:
The Chinese Journal of Clinical Pharmacology
2016;32(8):765-768
- CountryChina
- Language:Chinese
-
Abstract:
Warfarin is prone to cause thromboembolism or bleeding due to its narrow therapeutic window.Studies have shown that both genetic and environmental factors affect individual difference of warfarin dose.This review will summarize the recent progress of models building and valida-ting at home and abroad to provide a reference for individualized treat-ment of warfarin.
