New challenge of target-specific anticoagulants replacing warfarin
10.13699/j.cnki.1001-6821.2016.05.028
- VernacularTitle:靶向口服抗凝药给华法林带来的新思路
- Author:
Yun KUANG
1
;
Qing LAI
;
Shuang YANG
;
Li-Ying GONG
;
Yu-Xia XIANG
;
Jing-Le LI
;
Guo-Ping YANG
Author Information
1. 中南大学 药学院
- Keywords:
targeted oral anticoagulant drug;
warfarin;
atrial fibrilla-tion;
deep venous thrombosis
- From:
The Chinese Journal of Clinical Pharmacology
2016;32(5):473-475
- CountryChina
- Language:Chinese
-
Abstract:
Warfarin was the only oral anticoagulant drug , widely used in the prevention of thromboembolism events.The antithrombotic effect of warfarin has been very clear , but there are also some defects , such as that the treatment window is narrow and individual difference is very big.In recent years , the emergence of new targeted oral anticoagulant agents has provided a new choice for the anticoagulant drugs.The development of targeted oral anticoagulant drugs is reviewed , and the new challenge to warfarin is discussed.