Using Delphi method to determine the questions and outcomes included in the Practice Guidelines for Individualized Medication of voriconazole

VernacularTitle:用德尔菲法确定伏立康唑个体化用药指南临床问题与结局指标
Author: Ken CHEN ¹ ; Shu-Yao LIANG ; Ying-Ying YAN ; Yao-Long CHEN ; Suo-Di ZHAI ; Xiang-Lin ZHANG
Author Information

1. 北京大学第三医院药剂科
Keywords: voriconazole; guideline; Delphi; question; outcome
From: The Chinese Journal of Clinical Pharmacology 2016;(4):368-369,381
CountryChina
Language:Chinese
Abstract: Objective To define the questions and outcomes included in the Practice Guidelines for Individualized Medication of voriconazole and their importance ranking.Methods Using the Delphi method , experts were consulted in three rounds.Enthusiasm index , conformity indexes and authority indexes were calculated for quality control.Results Eighteen questions and 10 outcomes were defined.Recommendations of seven questions must be developed in the guideline.Four outcomes were ranked as “critical outcome”.Enthusiasm index was 90.5%.Authority indexes were all >0.75.Conformity indexes of only 2 questions and 2 outcomes were ≤15%.Conclusion Through Delphi method , questions and outcomes included in the Practice Guidelines for Individualized Medication of voriconazole were defined , which gives directions to guide-line development.