Analysis the safety of combined medication for elderly patients
10.13699/j.cnki.1001-6821.2015.24.032
- VernacularTitle:老年人合并用药的安全性分析
- Author:
Shuang ZHOU
1
;
Qian XIANG
;
Xia ZHAO
;
Ying ZHOU
;
Yi-Min CUI
Author Information
1. 北京大学第一医院药剂科
- Keywords:
polypharmacy;
elderly patient;
angiotensin converting enzyme inhibitor;
calcium channel blocker;
benzodiazepines;
sulfonylurea
- From:
The Chinese Journal of Clinical Pharmacology
2015;(24):2471-2473
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the research development of combined medication for elderly patients.Methods By reviewing the relevant lit-eratures, the status of elderly patients with drug use, pharmacokinetics and pharmacodynamic characteristics and the safety of drug use in the elderly patients with drug safety and safety issues were summarized and expounded.Results With the increase of age and physiological chan-ges, the pharmacokinetics and pharmacodynamics in elderly have changed, which affect the choice and safety of drug use for elderly pa-tients.Angiotensin converting enzyme inhibitors ( ACEI ) , benzodiaz-epines, calcium channel blockers (CCB) and sulfonylurea are commonly used in elderly common diseases, when combined with other drugs, they should be paid close attention to. Conclusion Prescription should follow the principle of rational drug use in elderly, in order to protect the safety and efficacy of medication for the elderly.
