Investigation of vancomycin used in geriatric patients
10.13699/j.cnki.1001-6821.2015.24.025
- VernacularTitle:万古霉素在老年患者中的临床用药调查分析
- Author:
Xiao-Yan SHENG
1
;
Fei-Fei GAO
;
Ling-Yue MA
;
Chao-Yang CHEN
;
Ying ZHOU
;
Yi-Min CUI
Author Information
1. 北京大学第一医院药剂科
- Keywords:
vancomycin;
therapeutic drug monitoring;
geriatric patients;
drug rational use
- From:
The Chinese Journal of Clinical Pharmacology
2015;(24):2451-2453
- CountryChina
- Language:Chinese
-
Abstract:
Objective This study is to investigate the use of vancomycin in geriatric patients and promote the safe and rational usage of vancomy-cin.Methods By retrospective analysis, data were extracted from medical records of 180 geriatric patients who intravenously used vancomy-cin in 2014 in terms of etiology check, diseases, therapeutic drug moni-toring, medication duration, therapeutic efficacy, etc. Results The treatment of vancomycin in 58.88%geriatric patients was based on expe-rience and 75.55% geriatric patients use vancomycin to treat infection instead of pretending infection and the effective rate was 38.89%.The biggest reason to use vancomycin was pulmonary infection ( 54.37%) , 87.78% of the patients completed etiology check and drug sensitive test, and staphylococcal infection accounts for 16.29%of the positive results, 29.44% of the patients completed therapeutic drug monitoring. Conclusion Most of the usage is rational.The time of treatment is still to be discussed.The treatment is mainly based on the experience.Thera-peutic drug monitoring ( TDM ) is under specification.Clinical pharma-cists should try to make the monitor time in clinic and the application of vancomycin in the geriatric patients more reasonable .