Self-made vancomycin quality-control serum applied in blood drug concentration monitoring
10.13699/j.cnki.1001-6821.2015.22.024
- VernacularTitle:自制万古霉素质控血清用于血药浓度监测的可行性探讨
- Author:
Fu-Xiang DONG
1
;
Ai-Ling MA
;
Yu-Hua QIN
Author Information
1. 河南省人民医院药学部
- Keywords:
vancomycin;
blood drug concentration;
quality control
- From:
The Chinese Journal of Clinical Pharmacology
2015;31(22):2252-2253
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate self -made vancomycin quality -control serum used in blood drug concentration monitoring .Methods To prepare 10,20,30 μg·mL-1 vancomycin quality -control serum. The preparation, repeatability, sample stability and clinical application were studied.Results The results of low, medium and high concentra-tion of vancomycin quality-control serum was 98.0%-101.5%.The content change of vancomycin was less than 2% while saved at -30 ℃within 6 months.Conclusion The method for preparation of self-made vancomycin quality-control serum is simple, cost-effective, accurate and reliable, which can be used as daily laboratory quality control saved at -30℃.
