Effect of early high -volume hemofiltration in the treatment and prognosis of post-resuscitation syndrome
10.13699/j.cnki.1001-6821.2015.22.006
- VernacularTitle:早期高容量血液滤过对心肺复苏后综合征患者预后的影响
- Author:
Qian-Long XUE
1
;
Hui WANG
;
Ying HE
;
Shu-Chi HAN
;
Li-Peng YANG
;
Yan-Mei CHEN
;
Xiu-Qian ZHANG
;
Fan LIU
Author Information
1. 河北北方学院 附属第一医院 急诊科
- Keywords:
early stage;
high volume hemofiltration;
post-resuscitation syndrome;
prognosis;
influence
- From:
The Chinese Journal of Clinical Pharmacology
2015;31(22):2196-2198
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of early high -volume hemofiltration in the treatment and prognosis of post -resuscitation syndrome( PRS).Methods A total of 44 patients wiht PRS were ran-domly divided into the trial group and the control group, and all patients were treated by conventional treatment.The patients in the trial group were treated by early high-volume hemofiltration within 6 h, while the patients in the control group were treated by high-volume hemofiltration after 6 h.Acute physiology and chronic health evaluation ( APACHEII) , multiple organ dysfunction syndrome evaluation ( MODS ) , C -reactive protein(CRP), procalcitonin(PCT), dopamine dosage, mean arterial pressure(MAP), and oxygenation index were recorded.Results The APACHE Ⅱ score, MODS score, serum CRP and PCT level improved and dopamine dosage decreased after treatment in two groups compared with those before treatment (P<0.05), but the parameters in trial group were significantly lower than those in control group ( P<0.05) , and MAP and oxygenation index in the trial group were significantly higher than those in the control group ( P <0.05 ) . Conclusion Early high-volume hemofiltration is effective in the treatment and prognosis of PRS with positive significance.
