Clinical efficacy and safety of Qianlieshutong capsule combined with levofloxacin in treatment of chronic bacteritic prostatitis
10.13699/j.cnki.1001-6821.2015.22.003
- VernacularTitle:前列舒通联合左氧氟沙星治疗慢性细菌性前列腺炎的临床疗效及安全性评价
- Author:
Cai-Yun YANG
1
;
Jin-Chun QI
;
Wen-Yong XUE
Author Information
1. 河北医科大学 第二医院
- Keywords:
Qianlieshutong;
levofloxacin;
prostatitis;
clinical efficacy;
safety
- From:
The Chinese Journal of Clinical Pharmacology
2015;31(22):2187-2189
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical efficacy and safety of the combination of Qianlieshutong and levofloxacin in the treatment of pa-tients with chronic bacterial prostatitis.Methods One hundred thirty-five patients with chronic bacterial prostatitis were randomly divided into treatment group (n=71) and control group (n=64).Patients in treat-ment group were treated with qianlieshutong 0.4 g, po, 3 times a day and levofloxacin 0.1 g, twice a day.Patients in control group were trea-ted with levofloxacin 0.1 g, twice a day.The course of treatment was 2 weeks in two groups.The clinical efficacy, bacteriological efficacy and incidence of adverse drug reactions between the two groups were com-pared.Results The effective rate of treatment group ( 60.56%) was significantly higher than that of control group (51.56%, P<0.05).The bacterial clear rate of treatment group ( 100.00%) was significantly higher than that of control group ( 72.22%, P<0.05 ) .The incidences of adverse reactions were 4.23%and 3.13%in the treatment group and control group respectively without statistical difference ( P >0.05 ) . Conclusion The clinical efficacy of Qianlieshutong combine with levofloxacin in the treatment of prostatitis is exact, and without increasing incidence of adverse drug reactions.
