Clinical study of traditional Chinese medicine retention enema in the treatment of acute severe pancreas
10.13699/j.cnki.1001-6821.2015.18.010
- VernacularTitle:中药保留灌肠在重症胰腺炎急性期的临床研究
- Author:
Jian-Bin SHEN
1
;
Zong-Li WANG
Author Information
1. 湖州市第一人民医院 普外科
- Keywords:
Qingyi chengqi soup;
retention enema;
acute severe pancreas;
inflammatory factor
- From:
The Chinese Journal of Clinical Pharmacology
2015;(18):1831-1833
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigated clinical effect and safety of tradi-tional Chinese medicine ( TCM) retention enema in the treatment of acute severe pancreas.Methods A total of 62 cases of severe acute pancreati-tis patients enrolled for the study were randomly divided into experiment group and control group , 31 patients in the control group received con-ventional treatment , patients in experiment group received the TCM retention enema on the basis of the conventional treatment , one dose a day, twice per 100 mL, 10 d course of treatment.Clinical symptoms ( abdominal bloating relief time , bowel recovery time ) , inflammatory factors(TNF-α, LPS), a therapeutic effect of the two groups were com-pared.Results The efficacy of experiment group was 93.55%, signifi-cantly higher than that of control group with efficacy 74.19%(P<0.05).Abdominal pain time, time to ease bloating, and bowel re-covery time , hospital stay , TNF-α, endotoxin ( LPS ) , complications and mortality of experiment group were significantly lower than those of the control group ( P <0.05 ) .Conclusion TCM retention enema is helpful to improve the clinical symptoms , reduce inflammatory factor expression and improve the effect of treatment .
