Analysis on the chemical and biological products suitable for children in National Essential Medicine List (2012 edition)
10.13699/j.cnki.1001-6821.2015.17.025
- VernacularTitle:《国家基本药物目录》(2012年版)中适宜儿童使用的化学药品和生物制品的分析
- Author:
Zhe CHEN
1
;
Xiao-Hui XIE
;
Xiao-Ling WANG
;
Chun-Yan GUO
;
Yan-Ju ZHANG
;
Bo-Yang HU
;
Xiao-Chuan WANG
;
Jia-Yu CUI
Author Information
1. 北京大学 药学院
- Keywords:
essential medicine list;
child;
suitability;
active ingredient;
formulation;
dosage form;
strength
- From:
The Chinese Journal of Clinical Pharmacology
2015;(17):1786-1788
- CountryChina
- Language:Chinese
-
Abstract:
Objective To demonstrate the chemical and biological prod-ucts suitable for children in National Essential Medicine List (2012 Edi-tion)(NEML).Methods The active ingredients and formulations sui-table for children in NEML were demonstrated based on the latest version of instructions , ‘Chinese National Formulary ( Chemicals and Biological Products for Children ) ’ , the fourth edition ‘World Health Organization (WHO) Model List of Essential Medicines for Children ’, the results of literature and the suggestions from clinic experts.List the dosage forms , formulations and strengths suitable for children of different ages.Results The amount of active ingredients suitable for children are 283 , accounting for 91.59%.The proportion of formulations and strengths suitable for children of different ages: less than 2 years old is 44.29%and 28.14% respectively , 2 -5 years old is 76.30% and 50.06%respectively , more than 5 years old is 84.95%and 80.60% respective-ly.Conclusion Chemical and biological products in NEML provide important safeguard for children , but the dosage forms and strengths are not enough for young children.