Circadian rhythm of drug process in vivo and its application in disease treatment
10.13699/j.cnki.1001-6821.2015.15.028
- VernacularTitle:药物体内过程的昼夜节律在临床疾病治疗中的应用
- Author:
Dai-Rong ZHANG
1
;
Zao-Qin YU
;
Cheng-Liang ZHANG
;
Dong LIU
Author Information
1. 华中科技大学同济医学院附属同济医院药学部
- Keywords:
drug process in vivo;
circadian rhythm;
chronopharmaceuti-cal delivery;
drug therapy
- From:
The Chinese Journal of Clinical Pharmacology
2015;(15):1558-1560
- CountryChina
- Language:Chinese
-
Abstract:
The process of drug in vivo is influenced by the circadian rhythm, which may cause circadian variation in drug efficacy and toxici-ty.This study mainly reviewed the circadian rhythm of drug kinetic processes such as absorption, distribution, metabolism and excretion of drug.Moreover, Authors also described the application of circadian rhythm in the treatment of disease.
