Clinical efficacy of good intelligence prescription combined piracetam on Alzheimer′s disease patients
10.13699/j.cnki.1001-6821.2015.15.012
- VernacularTitle:益智治呆方联合吡拉西坦治疗老年痴呆症的临床研究
- Author:
Cui-Xia ZHAO
1
;
A clothing Nur wood Ahmat buck
;
Zhi WAN
;
Yu JIANG
;
Go-Li SEN
Author Information
1. 新疆医科大学附属中医医院
- Keywords:
perception of enhancing intelligence and treating dementia;
dementia;
piracetam;
memory
- From:
The Chinese Journal of Clinical Pharmacology
2015;(15):1506-1508
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe and study the efficacy and the impact on memory of alzheimer′s disease patients treated with perception of enhancing intelligence and treating dementia.Methods A total of 114 cases of alzheimer′s patients were randomly divided into treatment group (57 cases) and control group (57 cases).Patients in control group were treated with piracetam, oral 0.8 -1.6 g, 4 times a day.Patients in treatment group were taken perception of enhancing intelligence and treating dementia on the basis of control group, 2 times a day, 4 weeks for a course of treatment.Before and after three months treatment, MMSE, BI, and cognitive function, memory and Blessed dementia scale were assess.Clinical efficacy and adverse reactions of the two groups were observed.Results Total effective rate in treatment group was 94.74%, significantly higher than that in control group, which was 63.15%( P<0.05 ).After treatment, MMSE score ( 17.5 ±2.1 ) and BI score (74.9 ±5.7) in control group were significantly lower than that in treatment group, which were ( 22.2 ±2.3 ) , ( 85.8 ±5.9 ) , ( P<0.05).After treatment, cognitive function, vocabulary and memory in treatment group were significantly higher than that in control group.The Blessed dementia scale score in treatment group (4.6 ±2.4) was lower than that in control group (5.8 ±2.5).The incidence of adverse reactions in treatment group(7.01%), was lower than that in control group(28.07%, P<0.05).Conclusion Perception of enhancing intelligence and treating dementia combined piracetam can effectively improve the clinical symptoms, memory and life skills of alzheimer′s patients.
