Effect of Kai Hou Jian -spray combined with drugs on herpetic stomatitis in children
10.13699/j.cnki.1001-6821.2015.12.014
- VernacularTitle:药物治疗配合开喉剑喷剂治疗小儿疱疹性口腔炎的临床研究
- Author:
Ya-Qiong LIU
1
;
Qin-Yu YANG
;
Jia CHEN
;
Jian XIE
;
Jing YU
Author Information
1. 绵阳市中心医院儿科
- Keywords:
Kai Hou Jian-spray;
herpetic stomatitis;
children
- From:
The Chinese Journal of Clinical Pharmacology
2015;(12):1121-1123
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of Kai Hou Jian-spray in treating herpetic stomatitis of children.Methods A total of 180 children who suffered herpetic stomatitis were randomly divided into treatment group and control group, 90 cases in each group.Patients in control group were given routine treatment scheme such as oral care and water-electrolyte balance,and on the basis of control group, those in treatment group were extra given Kai Hou Jian-spray every 3 to 4 hours and 6 to 7 spray each time.The treatment lasted for 5 to 7 days.And the clinical effects (effective, markedly effective, invalid and total effective rate), signs of symptoms ( the recovery time of body temperature, the disappea-rance time of oral herpes and the hospitalization time ) and adverse reac-tions were observed and compared.Results Compared with control group, the disappearing time of clinical symptoms and the hospitalization time were significantly decreased in a shorter time in treatment group (P<0.05).The total effective rate in treatment group was 95.55%, significantly higher than 77.78% in the control group ( P <0.01 ) . Conclusion Kai Hou Jian -spray combined with drug treatment has significant effect on herpetic stomatitis in children , with a shorter hospitalization time and disappearance time of oral herpes.
