Distribution and antibiotic susceptibility of pathogenic stains in blood culture with 1724 samples in our hospital
10.13699/j.cnki.1001-6821.2015.11.035
- VernacularTitle:本院1724份血培养病原菌的分布及耐药性分析
- Author:
Jun-Na ZHU
1
;
Chun-Hua QIE
;
Hong-Zhang WU
Author Information
1. 天津市第二人民医院检验科
- Keywords:
blood culture;
pathogen;
drug resistance;
gram -positive organism;
gram-negative organism
- From:
The Chinese Journal of Clinical Pharmacology
2015;(11):1053-1055
- CountryChina
- Language:Chinese
-
Abstract:
Objective To provide evidence for rationally selection of an-tibiotic agents, we investigated the distribution and antibiotic susceptibili-ty of pathogenic stains in blood culture in Tianjin Second People′s Hospi-tal.Methods Blood specimens were cultured with BacT/Alert 3D.The pathogenic bacterial confirmatory and antibiotic susceptibility tests were carried out with VETEK -2 COMPACT.Results From June 2011 to May 2013 , 225 strains of pathogenic bacteria were isolated from 1724 clinic blood specimens, of which 155 strains were gram-negative cocci, acounting for 68.9%;69 strains were gram-positive cocci,acounting for 30.7%;1 strains were fungi, acounting for 0.4%.The sensitivity of Gram-negative bacteria to imipenem was the highest.The sensitivity of Gram -positive bacteria to vancomycin and linezolid was the highest.Escherichia coli is highly resistant to ampicillin, with the resistance rate of 80.1%.Staphylococcus aureus resistance of penicillin with resistant rate of 57.1%.Conclusion It is important for the clinicals to get the results of distribution and antibiotic susceptibility of pathogenic stains in blood culture in order to select the antibiotics rationally and decrease nosocomial infections.