Resistance analysis of clinical isolated bacteria during 2014 in our hospital
10.13699/j.cnki.1001-6821.2015.11.033
- VernacularTitle:本院2014年临床分离菌耐药性分析
- Author:
Chang-Xiu NING
1
;
Xi-Rong QIU
;
Li-Min HU
Author Information
1. 抚州市第一人民医院 检验科
- Keywords:
bacteria;
antimicrobial agent;
drug sensitive test;
resistance;
monitor
- From:
The Chinese Journal of Clinical Pharmacology
2015;(11):1044-1048
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the antimicrobial resistance of clini-cal isolates in Fuzhou First People′s Hospital during 2014.Methods The identification and antimicrobial susceptibilities of these isolates both employed the ATB reader semi automatic equipment by colorimetric method.The interpretation of results refer to the CLSI 2013.All data were analyzed by WHONET 5.5 software.Results A total of 885 non-duplicate clinical isolates were collected during 2014.Including gram-negative bacterias ( 529, 59.8%), gram -positive bacterias ( 263, 29.7%) and fungus ( 93 , 10.5%).The prevalence of ESBLs was 36.3%in Escherichia coli and and 19.3%in Klebsiella spp.( Klebsiella pneumoniae and Klebsiella oxytoca ) . The drug resistance of Enterobacteriaceae bacteria to meropenem and imipenem were less than 10%.Drug resistance rate of imipenem was 17% in Pseudomonas aeruginosa isolates,The resistance rates to all the drug tested were greater than 50%in Acinetobacter baumannii strains except for polymyxin E ( less than 10%) .The detection rate of multi -drug resistance Acinetobacter baumannii was 75.9%.The prevalence of MRSA and MRCNS was 63%and 71.4% in respectively each strain, no vancomycin resistant Staphylococcus aureus was found, 1 identified Enterococcus faecium was resistant to vancomycin.Conclusion The majority of clinical isolates in our hospital were gram-negative bacilli, bacterial resistance remains a clinical important problem in, particularly of the detection rate of MRSA was higher than that of other regions in China, which should be concerned high attention.
