Bacterial distribution and resistance in biliary tract infections of the tertiary hospitals of China in 2012
10.13699/j.cnki.1001-6821.2015.11.031
- VernacularTitle:2012年全国三级医院胆汁培养病原菌的构成及耐药性分析
- Author:
Zhi SUN
1
;
Peng-Yuan WANG
;
LI-wei
;
Chao YAN
;
Yu-Cun LIU
;
Hui PAN
;
Xue-Song XU
Author Information
1. 吉林大学 中日联谊医院 检验科
- Keywords:
biliary tract infection;
pathogens;
antibiotic;
resistance
- From:
The Chinese Journal of Clinical Pharmacology
2015;(11):1038-1041
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand the bacteria distribution of biliary tract infections and drug resistance in China.Methods Antimicrobial susceptibility test for strains isolated from bile culture were performed in 557 hospitals in china.WHONET 5.6 software was used for statistical analysis.Results A total of 13596 bacterial strains were isolated, inclu-ding gram-positive cocci 3698 strains, accounting for 27.2%, gram-negative bacilli 9898 strains, accounting for 72.8%.The top two gram-positive cocci are Enterococcus faecalis 1237 strains (9.1%) and Entero-coccus faecium 1198 strains (8.8%).The top three gram-negative ba-cilli are Escherichia coli 4311 strains ( 31.7%) , Klebsiella pneumoniae 1518 strains ( 11.2%) and Pseudomonas aeruginosa 839 strains (6.2%) .The highest resistant rates of Escherichia coli and Klebsiella pneumoniae is ampicillin, amounting to 79.0% -87.1%; The resis-tance rates to cefotaxime of Escherichia coli and Klebsiella pneumoniae were 70.6% and 55.8 % respectively, and the resistance rates to cefepime were 28.7% and 18.4% respectively.The sensitive rates to imipenem and meropenem of Pseudomonas aeruginosa were 61.1% and 65.7%respectively.The resistance rates to vancomycin of Enterococcus faecalis and Enterococcus faecium were 2.5% and 1.3% respectively. Conclusion The most common pathogens of biliary infections are Escherichia coli, Klebsiella pneumonia, Pseudomonas aeruginosa and other Enterobacteriaceae.
