Antimicrobial susceptibility pattern and epidemiology of bacteria isolated from peritoneal fluid in China in 2012
10.13699/j.cnki.1001-6821.2015.11.028
- VernacularTitle:2012年中国患者腹水标本分离细菌分布及敏感性分析
- Author:
Bo ZHENG
1
;
Yuan LV
;
Yi-Sheng PAN
;
Peng-Yuan WANG
;
Yu-Cun LIU
Author Information
1. 北京大学 第一医院
- Keywords:
peritoneal fluid;
bacteria;
antibiotics;
resistance;
surveillance
- From:
The Chinese Journal of Clinical Pharmacology
2015;(11):1022-1026
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the bacterial distribution and resis-tance to antibiotic isolated from peritoneal fluid in China, 2012.Methods The bacteria isolated from peritoneal fluid in the tertiary hospitals were routinely identified.Disc diffusion test, minimun ihibitory concentration ( MIC) test and E-test were used to detect the antimicro-bial sensitivi-ty.Results Total of 10252 pathogenic strains were collec-ted from peri-toneal fluid specimens from 557 tertiary hospitals, which included Esche-richia coli 3215 strains ( 31.4%) , Klebsiella pneumoniae 860 strains ( 8.4%) , Enterococcus faecium 730 strains ( 6.9%) , Pseu-domonas aeruginosa 548 strains ( 5.3%) and Staphylococcus epidermidis 531 strains (5.2%).The resistance rate of Staphylococcus aureus strains to oxacillin were 47.4%, no vancomycin and linezolide resistant isolate were found.The rates of susceptibility of Escherichia coli, Klebsiella pneumoniae and Enterobacter cloacaeisolates to ceftriaxone were 28.2%, 50.8%and 41.0%, respectively;to meropenem were 96.7%, 88.8%and 96.5%, respectively.The rates of susceptibility of Pseudomonas aeruginosa to carbapenem, ceftazidime and cefepime were >60%, to quinolone was >75%.The rates of susceptibility of Acinetobacter baumannii isolates to cabarpenem were <40%, to amikacin were 50.8%.Conclusions The two most common species from peritoneal fluid in tertiary hospital were Escherichia coli and Klebsiella pneumonia.There were some difference in bacterial resistance to different antibiotics.
