Analysis of pathogen distribution in patients with cervical cancer
10.13699/j.cnki.1001-6821.2015.11.017
- VernacularTitle:宫颈癌患者的病原菌分布分析
- Author:
Ya-Wen ZHANG
1
;
Yun CAI
Author Information
1. 兰溪市妇幼保健院 妇产科
- Keywords:
pathogenic bacteria;
human papilloma virus infection;
genital tract;
cervical cancer
- From:
The Chinese Journal of Clinical Pharmacology
2015;(11):957-959
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the distribution of reproductive tract infection pathogens in cervical cancer patients with high risk of the hu-man papilloma virus ( HPV).Methods A total of 355 cases that patho-logically confirmed as cervical cancer ( the observation group) were retro-spectively analyzed, and 538 patients with chronic cervicitis were select-ed as control group from the same period.Patients in two groups all re-ceived vaginal secretions pathogen culture and HPV-DNA testing before the diagnosis, and then the distribution of pathogens and HPV test results were compared.Results In the observation group, 214 cases were de-tected HPV-positive ( 60.28%) , 226 cases detected in control group (42.01%), and the difference was statistically significant (P<0.05). Fungus, gram-negative bacteria, and gram-positive bacteria were most frequently detected, and Candida albicans accounted for the major part in two groups.The pathogen detection rate and constitution ratio of the two groups were statistically different ( P <0.05 ) , as well as the results of HPV detection.The pathogen culture results of HPV-positive patients in two groups were statistically different( P<0.05).Conclusion Infection is a risk factor for cervical cancer occurrence, and genital tract pathogen together HPV infection increased the occurrence rate of cervical cancer.
