Pareto optimal analysis of 39 cases of adverse reactions induced by ribonucleic acidⅡ

VernacularTitle:39例注射用核糖核酸Ⅱ不良反应的 Pareto最优分析
Author: Xiao-Ning GUO ¹ ; Peng-Cheng GE ; Hua XIE ; Tian-Shu REN
Author Information

1. 沈阳军区总医院药剂科
Keywords: ribonucleic acid Ⅱ; adverse drug reaction; pareto optimal
From: The Chinese Journal of Clinical Pharmacology 2015;(10):888-889
CountryChina
Language:Chinese
Abstract: Objective To investigate the general pattern and character-istics of adverse drug reaction ( ADR) induced by ribonucleic acid Ⅱ. Methods Pareto optimal analysis was adopted to analyze 39 cases of ADR induced by ribonucleic acid Ⅱoccurred in our hospital from Octo-ber 2010 to January 2014.Results Among 39 cases of ADR reports , the majority were people aged 40-59 years old (66.7%) , and all were caused by intravenous route of administration .24 patients ( 61.6%) were treated with more than three kinds of drugs .Most of cases occurred after 16 minutes ( 64.1%) .The clinical manifestations of ADR were mainly lesions of skin and its appendages ( 46.2%) , followed by ana-phylactoid reaction (38.4%) .Conclusion Clinical doctors and phar-macists should understand the pattern and characteristics of ADR induced by ribonucleic acid Ⅱ, and strengthen monitoring of its use in order to reduce occurrence of ADRs.