Outcome of flurbiprofen axetil injection on patients with lumbar disc excision pain
10.13699/j.cnki.1001-6821.2015.10.011
- VernacularTitle:氟比洛芬酯注射液对椎间孔镜下髓核摘除术后镇痛的临床疗效
- Author:
Xiao-Jing LI
1
;
Pei-Pei CHEN
;
Huan-Huan CAI
;
Xi-Xi JIN
Author Information
1. 温州医科大学 附属第二医院 疼痛科
- Keywords:
flurbiprofen axetil;
lumbar disc herniation;
percutaneous lumbar discectomy;
analgesia;
C reactive protein
- From:
The Chinese Journal of Clinical Pharmacology
2015;(10):802-805
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the analgesic effects of flurbiprofen axetil injection on patients with protrusion of intervertebral disc pain and nursing.Methods Sixty -two patients received lumbar disc excision were enrolled and randomly divided into control group ( n=31 ) and treat-ment group ( n=31 ) .Analgesic with parecoxib sodium in control group and with flurbiprofen in treatment group .Preoperative or postoperative ave-rage artery pressure ( MAP ) and heart rate ( HR ) , visual analogue scale ( VAS ) , ramsay sedation scale ( RSS ) and postoperative serum C reactive protein( CRP) content and adverse drug reaction incidence were all recorded.Results The MAP, HR, VAS, RSS of two groups were showed no significant difference ( P >0.05 ) .The treatment group patients′serum content of CRP at postoperative 24 h was 15.12 mg? L-1 , significantly lower than the control group of 25.71 mg? L-1 ( P<0.05 ) .The adverse drug reactions incidence in treatment group was significantly lower than that of control group ( 6.5% vs 19.4%, P<0.05).Conclusion Flurbiprofen axetil injection used for lumbar disc herniation patients analgesia , does not change the analgesic effect , reducethe stress reaction of patients , the adverse drug reaction is also lower .
