Effect of glutamine on patients with systemic inflammatory response syndrome by strengthening parenteral nutrition
10.13699/j.cnki.1001-6821.2015.08.011
- VernacularTitle:谷氨酰胺强化肠外营养对全身炎症反应综合征患者影响的临床研究
- Author:
Song-Zhi WANG
1
;
Le-Jun WU
;
Ying-Qiu WU
;
Jian-You ZHU
Author Information
1. 乐清市第二人民医院 外科
- Keywords:
glutamine;
parenteral nutrition;
nutritional status;
immune function
- From:
The Chinese Journal of Clinical Pharmacology
2015;(8):618-620,634
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of glutamine on the nutritional status and inflammatory response by strengthening parenteral nutrition in patients after general surgery .Methods Forty patients with systemic inflammatory response syndrome ( SIRS ) in our hospital were selected , and all patients were randomly divided into treatment group and control group, with 20 cases in each group.Patients in treatment group were given glutamine to strengthen parenteral nutrition , while those in the control group received amino acid solution for parenteral nutrition .The treatment continued for one week .The data of level of hemoglobin , albu-min, transferrin and immunoglobulin (IgG, IgA, and IgM), as well as nutrition risk screening score and acute physiology , age and chronic health evaluation score in two groups before and after parenteral nutrition were recorded and compared .Results After parenteral nutrition , the data of hemoglobin ,albumin and transferrin in the treatment group were (116.5 ±9.2), (35.7 ±2.4) and (66.3 ±2.4) g? L-1, respective-ly, and (102.5 ±8.6), (30.8 ±2.2) and (59.6 ±2.1) g? L-1 in control group (P<0.05);after parenteral nutrition, the data of IgG, IgA, and IgM levels in the treatment group were significantly higher than those in the control group , and nutrition risk screening score and acute physiology and chronic health score were significantly lower than those in the control group (P <0.05).Conclusion The effect of glutamine parenteral nutrition on SIRS patients is significant , and it can im-prove patients′nutritional status and the immune function recovery .
